Major Achievements: Operations and business development Development of a positioning and communication strategy for the production technology of Cilian AG within the frame of strategy workshops for business plans and the financial rounds. Attracted in the management four financial rounds with private and international institutional investors (1st: 2 Mio. Euro, 2nd: 4,5 Mio. Euro, 3 rd: 1 Mio. Euro, 4th: 1,7 Mio. Euro), accompanied investment and shareholder agreements. LOIs, research contracts, proof of principle-, evaluation-, and research and service contracts with 3 big pharma partners and 2 biotech companies, licence- and patent transfer agreements with 2 big pharma partners. Research and Development: Hired and managed a highly qualified and successful team of 12 scientist and technicians, Inventor of 8 patent applications and 3 granted patents, R&D budget of about 7,5 Mio Euro, Hired four national grants for Cilian (TIP, BioChancePlus, ZIM) and an international grant (EU) with a total project volume of 4.5 Mio. Euro, Set up of two R&D laboratory locations, involved in the planning of a new 380 m2 research laboratory together with the Incubator Centre (Technology Park Münster GmbH), First biosafety study for Ciliates, first animal study for enzymes derived from Ciliates, first animal study for a vaccine derived from Ciliates. Major R&D breakthrough: Worldwide first expression and secretion of a functional human biopharmaceutical enzyme (DNase I) in Ciliates, Worldwide first animal study for an enteric-coated Ciliate enzyme preparation for the treatment of exocrine pancreatic insufficiency, First licence option of a new expression plattform to an international pharma company. Spezialgebiete:Special management know how: Accompanying the start up process from its early stage in an entrepreneurial manner within an interdisciplinary team. Fund raising e.g. author of the business plans and presentations to venture capitalists as well as other potential investors. Special scientific know how: Enzyme preparation for oral substitution therapy, continuous fermentation, purification of proteins, process improvement.
Biotechnology, Protein Chemistry, Protein Purification, R&D, Biopharmaceuticals, Pharmaceutical Industry, Vaccines, Purification, Fermentation, Start-ups, Venture Capital, Drug Discovery, Monoclonal Antibodies, Antibodies, Lifesciences, Immunology, Proteomics, Cell Biology, Molecular Biology, Business Development